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Brigitte Kieffer, Ph.D.
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Directrice scientifique, Institut Douglas
Professeure, Département de psychiatrie, Université McGill
Directrice, Chaire Monique H. Bourgeois de recherche sur les troubles envahissants du développement, Université McGill


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Publications

2003

Berrendero F., Mendizabal V., Murtra P., Kieffer B., Maldonado R. (2003). Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPgammaS binding in the brain of mu-, delta- and kappa-opioid receptor knockout mice, Eur J Neurosci, 18(8), 2197-202. En savoir plus.

Brillet K., Kieffer B., Massotte D. (2003). Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening, BMC Pharmacol, 3, 14. En savoir plus.

Castane A., Robledo P., Matifas A., Kieffer B., Maldonado R. (2003). Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice, Eur J Neurosci, 17(1), 155-9. En savoir plus.

Chefer V. I., Kieffer B., Shippenberg T. S. (2003). Basal and morphine-evoked dopaminergic neurotransmission in the nucleus accumbens of MOR- and DOR-knockout mice, Eur J Neurosci, 18(7), 1915-22. En savoir plus.

Decaillot F. M., Befort K., Filliol D., Yue S., Walker P., Kieffer B. (2003). Opioid receptor random mutagenesis reveals a mechanism for G protein-coupled receptor activation, Nat Struct Biol, 10(8), 629-36. En savoir plus.

Gaveriaux-Ruff C., Simonin F., Filliol D., Kieffer B. (2003). Enhanced humoral response in kappa-opioid receptor knockout mice, J Neuroimmunol, 134(1-2), 72-81. En savoir plus.

Jamot L., Matthes H. W., Simonin F., Kieffer B., Roder J. C. (2003). Differential involvement of the mu and kappa opioid receptors in spatial learning, Genes Brain Behav, 2(2), 80-92. En savoir plus.

Koob G. F., Roberts A. J., Kieffer B., Heyser C. J., Katner S. N., Ciccocioppo R., Weiss F. (2003). Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology, Recent Dev Alcohol, 16, 263-81. En savoir plus.

Lutfy K., Eitan S., Bryant C. D., Yang Y. C., Saliminejad N., Walwyn W., Kieffer B., Takeshima H., Carroll F. I., Maidment N. T., Evans C. J. (2003). Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors, J Neurosci, 23(32), 10331-7. En savoir plus.

Martin M., Matifas A., Maldonado R., Kieffer B. (2003). Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones, Eur J Neurosci, 17(4), 701-8. En savoir plus.

Morinville A., Cahill C. M., Esdaile M. J., Aibak H., Collier B., Kieffer B., Beaudet A. (2003). Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice, J Neurosci, 23(12), 4888-98. En savoir plus.

Oakley S. M., Toth G., Borsodi A., Kieffer B., Kitchen I. (2003). G-protein coupling of delta-opioid receptors in brains of mu-opioid receptor knockout mice, Eur J Pharmacol, 466(1-2), 91-8. En savoir plus.

Philippe D., Dubuquoy L., Groux H., Brun V., Chuoi-Mariot M. T., Gaveriaux-Ruff C., Colombel J. F., Kieffer B., Desreumaux P. (2003). Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation, J Clin Invest, 111(9), 1329-38. En savoir plus.

Romberg R., Sarton E., Teppema L., Matthes H. W., Kieffer B., Dahan A. (2003). Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and mu-opioid receptor deficient mice, Br J Anaesth, 91(6), 862-70. En savoir plus.

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