Researcher, Douglas Institute
Antoine Adamantidis, PhD, is investigating the functional wiring and dynamics of neural circuits controlling sleep and wake states. He is using a combination of state-of-the-art molecular, cellular and behavioural technologies, which include genetic mouse engineering, in vitro and in vivo electrophysiology, behavioural paradigms and the emerging field of optogenetics. Optogenetics combines optical and genetic methodologies to modulate the activity of neural circuitry at very high speed, in order to understand how information is processed in the brain.
His research findings may lead to a better understanding of how the brain controls sleep, attention and cognition. This may open new therapeutic strategies for the treatment of sleep disorders and neuropsychiatric illnesses associated with sleep disturbances.
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