Researcher, Douglas Institute
Aurélie Labbe is a biostatistician who specializes in statistical genetics and genetic epidemiology. More specifically, she devotes her efforts to developing a methodology for genetic data analysis using association, genetic linkage and microarray studies.
Aurélie Labbe seeks to identify the susceptibility genes for major psychiatric diseases such as schizophrenia, bipolar disorder, depression or attention deficit hyperactivity disorder (ADHD). While genes are known to be responsible for most of these diseases, uncovering the susceptibility genes remains an arduous task and scientists are faced with the challenge of replicating the results. One of the potential causes could lie in defining the phenotype under study (e.g. diagnosis of the disease), which might be influenced by multiple gene-gene interactions. Aurélie’s current projects focus on developing a method to “sub-type” a complex disease into several homogeneous “sub-diseases”. To do this, she relies on the measures of symptoms and other clinical measures associated with the disease. Among other things, this model takes into account the inter- and intra-family heterogeneity observed in such studies.
Aurélie Labbe is actively involved in research that focuses on redefining phenotypes in genetic studies to increase their detection power. She also seeks to develop methods that will help to understand how different genes associated with a particular disease interact with one another.
Frank B. Common Pavilion
6875, boulevard LaSalle