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Brigitte Kieffer, PhD
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Scientific director, Douglas Institute
Professor, Department of Psychiatry, McGill University
Chair, Monique H. Bourgeois in Pervasive Developmental Disorders


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Publications

2001

Befort K., Filliol D., Decaillot F. M., Gaveriaux-Ruff C., Hoehe M. R., Kieffer B. (2001). A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling, J Biol Chem, 276(5), 3130-7. Find out more.

Dahan A., Sarton E., Teppema L., Olievier C., Nieuwenhuijs D., Matthes H. W., Kieffer B. (2001). Anesthetic potency and influence of morphine and sevoflurane on respiration in mu-opioid receptor knockout mice, Anesthesiology, 94(5), 824-32. Find out more.

Gaveriaux-Ruff C., Filliol D., Simonin F., Matthes H. W., Kieffer B. (2001). Immunosuppression by delta-opioid antagonist naltrindole: delta- and triple mu/delta/kappa-opioid receptor knockout mice reveal a nonopioid activity, J Pharmacol Exp Ther, 298(3), 1193-8. Find out more.

Hutcheson D. M., Matthes H. W., Valjent E., Sanchez-Blazquez P., Rodriguez-Diaz M., Garzon J., Kieffer B., Maldonado R. (2001). Lack of dependence and rewarding effects of deltorphin II in mu-opioid receptor-deficient mice, Eur J Neurosci, 13(1), 153-61. Find out more.

Maldonado R., Severini C., Matthes H. W., Kieffer B., Melchiorri P., Negri L. (2001). Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene, Br J Pharmacol, 132(7), 1485-92. Find out more.

Morin-Surun M. P., Boudinot E., Dubois C., Matthes H. W., Kieffer B., Denavit-Saubie M., Champagnat J., Foutz A. S. (2001). Respiratory function in adult mice lacking the mu-opioid receptor: role of delta-receptors, Eur J Neurosci, 13(9), 1703-10. Find out more.

Peluso J., Gaveriaux-Ruff C., Matthes H. W., Filliol D., Kieffer B. (2001). Orphanin FQ/nociceptin binds to functionally coupled ORL1 receptors on human immune cell lines and alters peripheral blood mononuclear cell proliferation, Brain Res Bull, 54(6), 655-60. Find out more.

Roberts A. J., Gold L. H., Polis I., McDonald J. S., Filliol D., Kieffer B., Koob G. F. (2001). Increased ethanol self-administration in delta-opioid receptor knockout mice, Alcohol Clin Exp Res, 25(9), 1249-56. Find out more.

Sarton E., Teppema L. J., Olievier C., Nieuwenhuijs D., Matthes H. W., Kieffer B., Dahan A. (2001). The involvement of the mu-opioid receptor in ketamine-induced respiratory depression and antinociception, Anesth Analg, 93(6), 1495-500, table of contents. Find out more.

Simonin F., Slowe S., Becker J. A., Matthes H. W., Filliol D., Chluba J., Kitchen I., Kieffer B. (2001). Analysis of [3H]bremazocine binding in single and combinatorial opioid receptor knockout mice, Eur J Pharmacol, 414(2-3), 189-95. Find out more.

Skoubis P. D., Matthes H. W., Walwyn W. M., Kieffer B., Maidment N. T. (2001). Naloxone fails to produce conditioned place aversion in mu-opioid receptor knock-out mice, Neuroscience, 106(4), 757-63. Find out more.

Slowe S. J., Clarke S., Lena I., Goody R. J., Lattanzi R., Negri L., Simonin F., Matthes H. W., Filliol D., Kieffer B., Kitchen I. (2001). Autoradiographic mapping of the opioid receptor-like 1 (ORL1) receptor in the brains of mu-, delta- or kappa-opioid receptor knockout mice, Neuroscience, 106(3), 469-80. Find out more.

Zhou L., Rowley D. L., Mi Q. S., Sefcovic N., Matthes H. W., Kieffer B., Donovan D. M. (2001). Murine inter-strain polymorphisms alter gene targeting frequencies at the mu opioid receptor locus in embryonic stem cells, Mamm Genome, 12(10), 772-8. Find out more.

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