The Martin Lepage Laboratory is currently exploring several inter-related dimensions of schizophrenia through the use of various clinical, neurocognitive and neuroimaging techniques, such as:


  • MRI and fMRI
  • Diffusion Tensor Imaging (DTI)
  • rTMS
  • Neuropsychological testing
  • Cognitive behavioural therapy
  • Cognitive remediation

Our approach is motivated by a desire to better understand cognitive symptoms that often characterize schizophrenia (e.g. memory difficulties, avolition, anhedonia, poor insight, etc.) and to develop research programs that will have significant clinical applications.

More specifically, the laboratory studies:

  • Neurocognitive and neuroimaging markers of remission in first episode psychosis
  • Biological and psychological determinants of insight in schizophrenia
  • Memory dysfunctions and their neural substrates in schizophrenia
  • Cognitive behavioural therapy for social anxiety in schizophrenia
  • Cognitive remediation therapy in schizophrenia
  • Cognitive neuroscience of episodic memory in healthy subjects