Centre intégré universitaire de santé et de services sociaux de l’Ouest-de-l’Île-de-Montréal
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Brigitte Kieffer, PhD
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Scientific director, Douglas Institute
Professor, Department of Psychiatry, McGill University
Chair, Monique H. Bourgeois in Pervasive Developmental Disorders


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Publications

2014

Bardoni R., Tawfik V. L., Wang D., Francois A., Solorzano C., Shuster S. A., Choudhury P., Betelli C., Cassidy C., Smith K., de Nooij J. C., Mennicken F., O'Donnell D., Kieffer B., Woodbury C. J., Basbaum A. I., MacDermott A. B., Scherrer G. (2014). Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn, Neuron, 81(6), 1312-27. Find out more.

Becker J. A., Clesse D., Spiegelhalter C., Schwab Y., Le Merrer J., Kieffer B. (2014). Autistic-like syndrome in mu opioid receptor null mice is relieved by facilitated mGluR4 activity, Neuropsychopharmacology, 39(9), 2049-60. Find out more.

Charbogne P., Kieffer B., Befort K. (2014). 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse, Neuropharmacology, 76 Pt B, 204-17. Find out more.

Chu Sin Chung P., Boehrer A., Stephan A., Matifas A., Scherrer G., Darcq E., Befort K., Kieffer B. (2014). Delta opioid receptors expressed in forebrain GABAergic neurons are responsible for SNC80-induced seizures, Behav Brain Res, 278C, 429-434. Find out more.

Chu Sin Chung P., Keyworth H. L., Martin-Garcia E., Charbogne P., Darcq E., Bailey A., Filliol D., Matifas A., Scherrer G., Ouagazzal A. M., Gaveriaux-Ruff C., Befort K., Maldonado R., Kitchen I., Kieffer B. (2014). A Novel Anxiogenic Role for the Delta Opioid Receptor Expressed in GABAergic Forebrain Neurons, Biol Psychiatry. Find out more.

Cohen A., Whitfield T. W., Kreifeldt M., Koebel P., Kieffer B., Contet C., George O., Koob G. F. (2014). Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization, PLoS One, 9(5), e97216. Find out more.

Cui Y., Ostlund S. B., James A. S., Park C. S., Ge W., Roberts K. W., Mittal N., Murphy N. P., Cepeda C., Kieffer B., Levine M. S., Jentsch J. D., Walwyn W. M., Sun Y. E., Evans C. J., Maidment N. T., Yang X. W. (2014). Targeted expression of mu-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward, Nat Neurosci, 17(2), 254-61. Find out more.

Erbs E., Faget L., Scherrer G., Matifas A., Filliol D., Vonesch J. L., Koch M., Kessler P., Hentsch D., Birling M. C., Koutsourakis M., Vasseur L., Veinante P., Kieffer B., Massotte D. (2014). A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks, Brain Struct Funct. Find out more.

Gardon O., Faget L., Chu Sin Chung P., Matifas A., Massotte D., Kieffer B. (2014). Expression of mu opioid receptor in dorsal diencephalic conduction system: New insights for the medial habenula, Neuroscience, 277, 595-609. Find out more.

Grieder T. E., Herman M. A., Contet C., Tan L. A., Vargas-Perez H., Cohen A., Chwalek M., Maal-Bared G., Freiling J., Schlosburg J. E., Clarke L., Crawford E., Koebel P., Repunte-Canonigo V., Sanna P., Tapper A. R., Roberto M., Kieffer B., Sawchenko P. E., Koob G. F., van der Kooy D., George O. (2014). VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation, Nat Neurosci, 17(12), 1751-8. Find out more.

Lutz P. E., Ayranci G., Chu-Sin-Chung P., Matifas A., Koebel P., Filliol D., Befort K., Ouagazzal A. M., Kieffer B. (2014). Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence, Neuropsychopharmacology, 39(11), 2694-705. Find out more.

Megat S., Bohren Y., Doridot S., Gaveriaux-Ruff C., Kieffer B., Freund-Mercier M. J., Yalcin I., Barrot M. (2014). Kappa-opioid receptors are not necessary for the antidepressant treatment of neuropathic pain, Br J Pharmacol. Find out more.

Nozaki C., Nagase H., Nemoto T., Matifas A., Kieffer B., Gaveriaux-Ruff C. (2014). In vivo properties of KNT-127, a novel delta opioid agonist: receptor internalisation, antihyperalgesia and antidepressant effects in mice, Br J Pharmacol. Find out more.

Reiss D., Walter O., Bourgoin L., Kieffer B., Ouagazzal A. M. (2014). New automated procedure to assess context recognition memory in mice, Psychopharmacology (Berl). Find out more.

Vergnano A. M., Rebola N., Savtchenko L. P., Pinheiro P. S., Casado M., Kieffer B., Rusakov D. A., Mulle C., Paoletti P. (2014). Zinc dynamics and action at excitatory synapses, Neuron, 82(5), 1101-14. Find out more.

Yoo J. H., Bailey A., Borsodi A., Toth G., Matifas A., Kieffer B., Kitchen I. (2014). Knockout subtraction autoradiography: a novel ex vivo method to detect heteromers finds sparse KOP receptor/DOP receptor heterodimerization in the brain, Eur J Pharmacol, 731, 1-7. Find out more.

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