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Naguib Mechawar, PhD
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Director, Mood, Anxiety and Impulsivity-Related Theme, Douglas Institute
Director, Douglas - Bell Canada Brain Bank, Douglas Institute


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Publications

2012

Freemantle E., Lalovic A., Mechawar N., Turecki G. (2012). Age and haplotype variations within FADS1 interact and associate with alterations in fatty acid composition in human male cortical brain tissue, PLoS One, 7(8), e42696. Find out more.

Furuya T. K., Silva P. N., Payao S. L., Bertolucci P. H., Rasmussen L. T., De Labio R. W., Braga I. L., Chen E. S., Turecki G., Mechawar N., Mill J., Smith M. A. (2012). Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer's Disease patients, Neuroscience, 220, 41-6. Find out more.

Furuya T. K., da Silva P. N., Payao S. L., Rasmussen L. T., de Labio R. W., Bertolucci P. H., Braga I. L., Chen E. S., Turecki G., Mechawar N., Mill J., de Arruda Cardoso Smith M. (2012). SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer's Disease, Neurochem Int, 61(7), 973-5. Find out more.

Krantic S., Isorce N., Mechawar N., Davoli M.A., Vignault E., Albuquerque M., Chabot J. G., Moyse E., Chauvin J.P., Aubert I., McLaurin J., Quirion R. (2012). Hippocampal GABAergic neurons are susceptible to amyloid-beta toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model, J Alzheimers Dis, 29(2), 293-308. Find out more.

Labonte B., Suderman M., Maussion G., Navaro L., Yerko V., Mahar I., Bureau A., Mechawar N., Szyf M., Meaney M., Turecki G. (2012). Genome-wide Epigenetic Regulation by Early-Life TraumaGenome Epigenetic Regulation by Early-Life Trauma, Arch Gen Psychiatry, 69(7), 722-731. Find out more.

Labonte B., Yerko V., Gross J., Mechawar N., Meaney M., Szyf M., Turecki G. (2012). Differential Glucocorticoid Receptor Exon 1(B), 1(C), and 1(H) Expression and Methylation in Suicide Completers with a History of Childhood Abuse, Biol Psychiatry. Find out more.

Mahar I., Bagot R. C., Davoli M. A., Miksys S., Tyndale R. F., Walker C., Maheu M., Huang S. H., Wong T., Mechawar N. (2012). Developmental hippocampal neuroplasticity in a model of nicotine replacement therapy during pregnancy and breastfeeding, PLoS one, 7(5), e37219. Find out more.

Maussion G., Yang J., Yerko V., Barker P., Mechawar N., Ernst C., Turecki G. (2012). Regulation of a truncated form of tropomyosin-related kinase B (TrkB) by Hsa-miR-185* in frontal cortex of suicide completers, PLoS ONE, 7(6), e39301. Find out more.

Mechawar N. (2012). [What can microscopy teach us on suicide?], Santé Ment Qué, 37(2), 57-64. Find out more.

Turecki G., Ernst C., Jollant F., Labonte B., Mechawar N. (2012). The neurodevelopmental origins of suicidal behavior, Trends Neurosci, 35(1), 14-23. Find out more.

Yu W., Mechawar N., Krantic S., Chabot J.G., Quirion R. (2012). Upregulation of astrocytic alpha7 nicotinic receptors in Alzheimer's disease brain- possible relevant to amyloid pathology, Mol Neurodegener, 7 Suppl 1, 07. Find out more.

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Awards and distinctions :
  • - CIHR New Investigator Award
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